Development of novel aminoglycoside (NB54) with reduced toxicity and enhanced suppression of disease-causing premature stop mutations

Lignende værker

• Suppression of CFTR premature termination codons and rescue of CFTR protein and function by the synthetic aminoglycoside NB54
  af: Rowe, Steven M., et al.
  Udgivet: (2011)
• Characterization of new-generation aminoglycoside promoting premature termination codon readthrough in cancer cells
  af: Bidou, Laure, et al.
  Udgivet: (2017)
• Overexpression and Initial Characterization of the Chromosomal Aminoglycoside 3′-O-Phosphotransferase APH(3′)-IIb from Pseudomonas aeruginosa
  af: Hainrichson, Mariana, et al.
  Udgivet: (2007)
• A comparative evaluation of NB30, NB54 and PTC124 in translational read-through efficacy for treatment of an USH1C nonsense mutation
  af: Goldmann, Tobias, et al.
  Udgivet: (2012)
• Aminoglycoside-Induced Premature Stop Codon Read-Through of Mucopolysaccharidosis Type I Patient Q70X and W402X Mutations in Cultured Cells
  af: Kamei, Makoto, et al.
  Udgivet: (2013)