Pathways Contributing to Development of Spontaneous Mammary Tumors in BALB/c-Trp53(+/−) Mice

Mutation and loss of function in p53 are common features among human breast cancers. Here we use BALB/c-Trp53(+/−) mice as a model to examine the sequence of events leading to mammary tumors. Mammary gland proliferation rates were similar in both BALB/c-Trp53(+/−) mice and wild-type controls. In add...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Yan, Haoheng, Blackburn, Anneke C., McLary, S. Christine, Tao, Luwei, Roberts, Amy L., Xavier, Elizabeth A., Dickinson, Ellen S., Seo, Jae Hong, Arenas, Richard B., Otis, Christopher N., Cao, Qing J., Lawlor, Rebecca G., Osborne, Barbara A., Kittrell, Frances S., Medina, Daniel, Jerry, D. Joseph
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Investigative Pathology 2010
Pynciau:
Regular Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832161/
https://ncbi.nlm.nih.gov/pubmed/20110418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090438
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