Pathways Contributing to Development of Spontaneous Mammary Tumors in BALB/c-Trp53(+/−) Mice

Mutation and loss of function in p53 are common features among human breast cancers. Here we use BALB/c-Trp53(+/−) mice as a model to examine the sequence of events leading to mammary tumors. Mammary gland proliferation rates were similar in both BALB/c-Trp53(+/−) mice and wild-type controls. In add...

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Bibliografski detalji
Glavni autori: Yan, Haoheng, Blackburn, Anneke C., McLary, S. Christine, Tao, Luwei, Roberts, Amy L., Xavier, Elizabeth A., Dickinson, Ellen S., Seo, Jae Hong, Arenas, Richard B., Otis, Christopher N., Cao, Qing J., Lawlor, Rebecca G., Osborne, Barbara A., Kittrell, Frances S., Medina, Daniel, Jerry, D. Joseph
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2010
Teme:
Regular Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832161/
https://ncbi.nlm.nih.gov/pubmed/20110418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090438
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