Pathways Contributing to Development of Spontaneous Mammary Tumors in BALB/c-Trp53(+/−) Mice

Mutation and loss of function in p53 are common features among human breast cancers. Here we use BALB/c-Trp53(+/−) mice as a model to examine the sequence of events leading to mammary tumors. Mammary gland proliferation rates were similar in both BALB/c-Trp53(+/−) mice and wild-type controls. In add...

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Detalhes bibliográficos
Main Authors: Yan, Haoheng, Blackburn, Anneke C., McLary, S. Christine, Tao, Luwei, Roberts, Amy L., Xavier, Elizabeth A., Dickinson, Ellen S., Seo, Jae Hong, Arenas, Richard B., Otis, Christopher N., Cao, Qing J., Lawlor, Rebecca G., Osborne, Barbara A., Kittrell, Frances S., Medina, Daniel, Jerry, D. Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832161/
https://ncbi.nlm.nih.gov/pubmed/20110418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090438
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