Pathways Contributing to Development of Spontaneous Mammary Tumors in BALB/c-Trp53(+/−) Mice

Mutation and loss of function in p53 are common features among human breast cancers. Here we use BALB/c-Trp53(+/−) mice as a model to examine the sequence of events leading to mammary tumors. Mammary gland proliferation rates were similar in both BALB/c-Trp53(+/−) mice and wild-type controls. In add...

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Autori principali: Yan, Haoheng, Blackburn, Anneke C., McLary, S. Christine, Tao, Luwei, Roberts, Amy L., Xavier, Elizabeth A., Dickinson, Ellen S., Seo, Jae Hong, Arenas, Richard B., Otis, Christopher N., Cao, Qing J., Lawlor, Rebecca G., Osborne, Barbara A., Kittrell, Frances S., Medina, Daniel, Jerry, D. Joseph
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2010
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Regular Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832161/
https://ncbi.nlm.nih.gov/pubmed/20110418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090438
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