Development of Spontaneous Mammary Tumors in BALB/c p53 Heterozygous Mice : A Model for Li-Fraumeni Syndrome

Breast cancer is the most frequent tumor type among women in the United States and in individuals with Li-Fraumeni syndrome. The p53 tumor suppressor gene is altered in a large proportion of both spontaneous breast malignancies and Li-Fraumeni breast cancers. This suggests that loss of p53 can accel...

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Bibliografski detalji
Glavni autori: Kuperwasser, Charlotte, Hurlbut, Gregory D., Kittrell, Frances S., Dickinson, Ellen S., Laucirica, Rudy, Medina, Daniel, Naber, Stephen P., Jerry, D. Joseph
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2000
Teme:
Animal Models
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885755/
https://ncbi.nlm.nih.gov/pubmed/11106587
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