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Reactive flux and folding pathways in network models of coarse-grained protein dynamics

The reactive flux between folded and unfolded states of a two-state protein, whose coarse-grained dynamics is described by a master equation, is expressed in terms of the commitment or splitting probabilities of the microstates in the bottleneck region. This allows one to determine how much each tra...

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Detalles Bibliográficos
Main Authors: Berezhkovskii, Alexander, Hummer, Gerhard, Szabo, Attila
Formato: Artigo
Idioma:Inglês
Publicado: U.S. Government 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832055/
https://ncbi.nlm.nih.gov/pubmed/19485483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.3139063
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