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Diffusion-influenced ligand binding to buried sites in macromolecules and transmembrane channels
We consider diffusion-influenced binding to a buried binding site that is connected to the surface by a narrow tunnel. Under the single assumption of an equilibrium distribution of ligands over the tunnel cross section, we reduce the calculation of the time-dependent rate coefficient to the solution...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Institute of Physics
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3172035/ https://ncbi.nlm.nih.gov/pubmed/21861586 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.3609973 |
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