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Role of diffusion in ligand binding to macromolecules and cell-bound receptors.

The association and dissociation rates of partially diffusion-controlled bimolecular reactions are considered. A simple expression for the equilibrium constant is derived using classical statistical mechanics. The relationship is established between the Collins-Kimball treatment, which is based on t...

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Bibliographic Details
Main Authors: Shoup, D, Szabo, A
Format: Artigo
Language:Inglês
Published: 1982
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1328970/
https://ncbi.nlm.nih.gov/pubmed/7139033
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