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Effect of ligand diffusion on occupancy fluctuations of cell-surface receptors

The role of diffusion in the kinetics of reversible ligand binding to receptors on a cell surface or to a macromolecule with multiple binding sites is considered. A formalism is developed that is based on a Markovian master equation for the distribution function of the number of occupied receptors c...

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Detalhes bibliográficos
Main Authors: Berezhkovskii, Alexander M., Szabo, Attila
Formato: Artigo
Idioma:Inglês
Publicado em: U.S. Government 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3739832/
https://ncbi.nlm.nih.gov/pubmed/24089722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.4816105
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