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Error and efficiency of replica exchange molecular dynamics simulations

We derive simple analytical expressions for the error and computational efficiency of replica exchange molecular dynamics (REMD) simulations (and by analogy replica exchange Monte Carlo simulations). The theory applies to the important case of systems whose dynamics at long times is dominated by the...

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Detalhes bibliográficos
Main Authors: Rosta, Edina, Hummer, Gerhard
Formato: Artigo
Idioma:Inglês
Publicado em: U.S. Government 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2780465/
https://ncbi.nlm.nih.gov/pubmed/19894977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.3249608
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