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Reactive flux and folding pathways in network models of coarse-grained protein dynamics
The reactive flux between folded and unfolded states of a two-state protein, whose coarse-grained dynamics is described by a master equation, is expressed in terms of the commitment or splitting probabilities of the microstates in the bottleneck region. This allows one to determine how much each tra...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
U.S. Government
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2832055/ https://ncbi.nlm.nih.gov/pubmed/19485483 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.3139063 |
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