Culture-Modified Bone Marrow Cells Attenuate Cardiac and Renal Injury in a Chronic Kidney Disease Rat Model via a Novel Antifibrotic Mechanism

BACKGROUND: Most forms of chronic kidney disease are characterized by progressive renal and cardiac fibrosis leading to dysfunction. Preliminary evidence suggests that various bone marrow-derived cell populations have antifibrotic effects. In exploring the therapeutic potential of bone marrow derive...

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Hlavní autoři: Yuen, Darren A., Connelly, Kim A., Advani, Andrew, Liao, Christine, Kuliszewski, Michael A., Trogadis, Judy, Thai, Kerri, Advani, Suzanne L., Zhang, Yuan, Kelly, Darren J., Leong-Poi, Howard, Keating, Armand, Marsden, Philip A., Stewart, Duncan J., Gilbert, Richard E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2010
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832011/
https://ncbi.nlm.nih.gov/pubmed/20209052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009543
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