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Early Outgrowth Cells Release Soluble Endocrine Antifibrotic Factors That Reduce Progressive Organ Fibrosis

Adult bone marrow-derived cells can improve organ function in chronic disease models, ostensibly by the release of paracrine factors. It has, however, been difficult to reconcile this prevailing paradigm with the lack of cell retention within injured organs and their rapid migration to the reticuloe...

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Detalhes bibliográficos
Publicado no:Stem Cells
Main Authors: Yuen, Darren A., Connelly, Kim A., Zhang, Yanling, Advani, Suzanne L., Thai, Kerri, Kabir, Golam, Kepecs, David, Spring, Christopher, Smith, Christopher, Batruch, Ihor, Kosanam, Hari, Advani, Andrew, Diamandis, Eleftherios, Marsden, Philip A., Gilbert, Richard E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5378495/
https://ncbi.nlm.nih.gov/pubmed/23922321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1502
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