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Early Outgrowth Cells Release Soluble Endocrine Antifibrotic Factors That Reduce Progressive Organ Fibrosis

Adult bone marrow-derived cells can improve organ function in chronic disease models, ostensibly by the release of paracrine factors. It has, however, been difficult to reconcile this prevailing paradigm with the lack of cell retention within injured organs and their rapid migration to the reticuloe...

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Publicat a:Stem Cells
Autors principals: Yuen, Darren A., Connelly, Kim A., Zhang, Yanling, Advani, Suzanne L., Thai, Kerri, Kabir, Golam, Kepecs, David, Spring, Christopher, Smith, Christopher, Batruch, Ihor, Kosanam, Hari, Advani, Andrew, Diamandis, Eleftherios, Marsden, Philip A., Gilbert, Richard E.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5378495/
https://ncbi.nlm.nih.gov/pubmed/23922321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1502
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