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HEXIM1 regulates E(2)/ERα-mediated expression of Cyclin D1 in mammary cells via modulation of P-TEFb

Estrogen receptor α (ERα) plays a key role in mammary gland development and is implicated in breast cancer through the transcriptional regulation of genes linked to proliferation and apoptosis. We previously reported that hexamethylene bisacetamide inducible protein 1 (HEXIM1) inhibits the activity...

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Bibliographische Detailangaben
Hauptverfasser: Ogba, Ndiya, Chaplin, Laura J., Doughman, Yong Qiu, Fujinaga, Koh, Montano, Monica M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2831806/
https://ncbi.nlm.nih.gov/pubmed/18757415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-0814
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