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HEXIM1 regulates E(2)/ERα-mediated expression of Cyclin D1 in mammary cells via modulation of P-TEFb

Estrogen receptor α (ERα) plays a key role in mammary gland development and is implicated in breast cancer through the transcriptional regulation of genes linked to proliferation and apoptosis. We previously reported that hexamethylene bisacetamide inducible protein 1 (HEXIM1) inhibits the activity...

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Detalhes bibliográficos
Main Authors: Ogba, Ndiya, Chaplin, Laura J., Doughman, Yong Qiu, Fujinaga, Koh, Montano, Monica M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2831806/
https://ncbi.nlm.nih.gov/pubmed/18757415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-0814
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