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The COXEN Principle: Translating signatures of in vitro chemosensitivity into tools for clinical outcome prediction and drug discovery in cancer

Substantial effort has been devoted to in vitro testing of candidate chemotherapeutic agents. In particular, the U.S. National Cancer Institute Developmental Therapeutics Program (NCI-DTP) Human Tumor Cell Line Screen has screened hundreds of thousands of compounds and extracts, for which data on mo...

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Autors principals: Smith, Steven C., Baras, Alexander S., Lee, Jae K., Theodorescu, Dan
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2831138/
https://ncbi.nlm.nih.gov/pubmed/20160033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-3562
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