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A strategy for predicting the chemosensitivity of human cancers and its application to drug discovery
The U.S. National Cancer Institute has used a panel of 60 diverse human cancer cell lines (the NCI-60) to screen >100,000 chemical compounds for anticancer activity. However, not all important cancer types are included in the panel, nor are drug responses of the panel predictive of clinical effic...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1941805/ https://ncbi.nlm.nih.gov/pubmed/17666531 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610292104 |
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