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In vitro transcriptomic prediction of hepatotoxicity for early drug discovery
Liver toxicity (hepatotoxicity) is a critical issue in drug discovery and development. Standard preclinical evaluation of drug hepatotoxicity is generally performed using in vivo animal systems. However, only a small number of preselected compounds can be examined in vivo due to high experimental co...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3386613/ https://ncbi.nlm.nih.gov/pubmed/21884709 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2011.08.009 |
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