Non-consensus GLI binding sites in Hedgehog target gene regulation

BACKGROUND: The GLI transcription factors, mediators of the hedgehog signal bind with high affinity to the consensus sequence GACCACCCA. The affinity of variant single substitutions in GLI binding sites has been measured systematically, but the affinities of the variant binding sites appears low com...

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Detalhes bibliográficos
Principais autores: Winklmayr, Martina, Schmid, Carmen, Laner-Plamberger, Sandra, Kaser, Alexandra, Aberger, Fritz, Eichberger, Thomas, Frischauf, Anna-Maria
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Research article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830928/
https://ncbi.nlm.nih.gov/pubmed/20070907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-11-2
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