Optimization of Time-Resolved Fluorescence Assay for Detection of Eu-DOTA-labeled Ligand-Receptor Interactions

Lanthanide-based luminescent ligand binding assays are superior to traditional radiolabel assays due to improved sensitivity and affordability in high throughput screening while eliminating the use of radioactivity. Despite significant progress using lanthanide(III)-coordinated chelators such as DTP...

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Bibliografiske detaljer
Main Authors: De Silva, Channa R., Vagner, Josef, Lynch, Ronald, Gillies, Robert J., Hruby, Victor J.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830854/
https://ncbi.nlm.nih.gov/pubmed/19852924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2009.10.031
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