Synthesis and Characterization of Time-resolved Fluorescence Probes for Evaluation of Competitive Binding to Melanocortin Receptors

Probes for use in time-resolved fluorescence competitive binding assays at melanocortin receptors based on the parental ligands MSH(4), MSH(7), and NDP-α-MSH were prepared by solid phase synthesis methods, purified, and characterized. The saturation binding of these probes was studied using HEK-293...

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Detalhes bibliográficos
Main Authors: Alleti, Ramesh, Vagner, Josef, Dehigaspitiya, Dilani Chathurika, Moberg, Valerie E., Elshan, N. G. R. D., Tafreshi, Narges K., Brabez, Nabila, Weber, Craig S., Lynch, Ronald M., Hruby, Victor J., Gillies, Robert J., Morse, David L., Mash, Eugene A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773999/
https://ncbi.nlm.nih.gov/pubmed/23890524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2013.06.052
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