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Origins of Regioselectivity and Alkene-Directing Effects in Nickel-Catalyzed Reductive Couplings of Alkynes and Aldehydes

Origins of regioselectivity and alkene-directing effects in nickel-catalyzed reductive coupling reactions were investigated by density functional calculations. Regioselectivity of simple alkynes is controlled by steric effects, while conjugated enynes and diynes are predicted to have increased react...

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Main Authors: Liu, Peng, McCarren, Patrick, Cheong, Paul Ha-Yeon, Jamison, Timothy F., Houk, K. N.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830786/
https://ncbi.nlm.nih.gov/pubmed/20095609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja909562y
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