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Identification of L-Methionine-S-Sulfoximine as the Convulsant Isomer of Methionine Sulfoximine

The convulsant agent methionine sulfoximine inhibits brain glutamine synthetase irreversibly and the inhibitor becomes bound to the active site of the enzyme as methionine sulfoximine phosphate. Only one of the four isomers of methionine sulfoximine, L-methionine-S-sulfoximine, inhibits glutamine sy...

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Bibliografske podrobnosti
Main Authors: Rowe, W. Bruce, Meister, Alton
Format: Artigo
Jezik:Inglês
Izdano: 1970
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC283073/
https://ncbi.nlm.nih.gov/pubmed/4393740
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