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Broad-minded links cell cycle-related kinase to cilia assembly and Hedgehog signal transduction

Recent findings indicate that mammalian Sonic hedgehog (Shh) signal transduction occurs within primary cilia, although the cell biological mechanisms underlying both Shh signaling and ciliogenesis have not been fully elucidated. We show that an uncharacterized TBC domain-containing protein, Broad-mi...

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Autori principali: Ko, Hyuk Wan, Norman, Ryan X., Tran, John, Fuller, Kimberly P., Fukuda, Mitsunori, Eggenschwiler, Jonathan T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830714/
https://ncbi.nlm.nih.gov/pubmed/20159594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2009.12.014
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