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Broad-minded links cell cycle-related kinase to cilia assembly and Hedgehog signal transduction

Recent findings indicate that mammalian Sonic hedgehog (Shh) signal transduction occurs within primary cilia, although the cell biological mechanisms underlying both Shh signaling and ciliogenesis have not been fully elucidated. We show that an uncharacterized TBC domain-containing protein, Broad-mi...

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Détails bibliographiques
Auteurs principaux: Ko, Hyuk Wan, Norman, Ryan X., Tran, John, Fuller, Kimberly P., Fukuda, Mitsunori, Eggenschwiler, Jonathan T.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830714/
https://ncbi.nlm.nih.gov/pubmed/20159594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2009.12.014
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