Hippi is essential for node cilia assembly and Sonic hedgehog signaling

Hippi functions as an adapter protein that mediates pro-apoptotic signaling from poly-glutamine-expanded huntingtin, an established cause of Huntington disease, to the extrinsic cell death pathway. To explore other functions of Hippi we generated Hippi knock-out mice. This deletion causes randomizat...

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Publicado en:Dev Biol
Main Authors: Houde, Caroline, Dickinson, Robin J., Houtzager, Vicky M., Cullum, Rebecca, Montpetit, Rachel, Metzler, Martina, Simpson, Elizabeth M., Roy, Sophie, Hayden, Michael R., Hoodless, Pamela A., Nicholson, Donald W.
Formato: Artigo
Idioma:Inglês
Publicado: 2006
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053816/
https://ncbi.nlm.nih.gov/pubmed/17027958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2006.09.001
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