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Hippi is essential for node cilia assembly and Sonic hedgehog signaling
Hippi functions as an adapter protein that mediates pro-apoptotic signaling from poly-glutamine-expanded huntingtin, an established cause of Huntington disease, to the extrinsic cell death pathway. To explore other functions of Hippi we generated Hippi knock-out mice. This deletion causes randomizat...
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| Publicado en: | Dev Biol |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2006
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5053816/ https://ncbi.nlm.nih.gov/pubmed/17027958 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2006.09.001 |
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