mNUDC is required for plus-end-directed transport of cytoplasmic dynein and dynactins by kinesin-1

Lissencephaly is a devastating neurological disorder caused by defective neuronal migration. The LIS1 (or PAFAH1B1) gene was identified as the gene mutated in lissencephaly patients, and was found to regulate cytoplasmic dynein function and localization. In particular, LIS1 is essential for anterogr...

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Autori principali: Yamada, Masami, Toba, Shiori, Takitoh, Takako, Yoshida, Yuko, Mori, Daisuke, Nakamura, Takeshi, Iwane, Atsuko H, Yanagida, Toshio, Imai, Hiroshi, Yu-Lee, Li-yuan, Schroer, Trina, Wynshaw-Boris, Anthony, Hirotsune, Shinji
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830693/
https://ncbi.nlm.nih.gov/pubmed/20019668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.378
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