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mNUDC is required for plus-end-directed transport of cytoplasmic dynein and dynactins by kinesin-1
Lissencephaly is a devastating neurological disorder caused by defective neuronal migration. The LIS1 (or PAFAH1B1) gene was identified as the gene mutated in lissencephaly patients, and was found to regulate cytoplasmic dynein function and localization. In particular, LIS1 is essential for anterogr...
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| 主要な著者: | , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2830693/ https://ncbi.nlm.nih.gov/pubmed/20019668 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.378 |
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