mNUDC is required for plus-end-directed transport of cytoplasmic dynein and dynactins by kinesin-1

Lissencephaly is a devastating neurological disorder caused by defective neuronal migration. The LIS1 (or PAFAH1B1) gene was identified as the gene mutated in lissencephaly patients, and was found to regulate cytoplasmic dynein function and localization. In particular, LIS1 is essential for anterogr...

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Detalhes bibliográficos
Main Authors: Yamada, Masami, Toba, Shiori, Takitoh, Takako, Yoshida, Yuko, Mori, Daisuke, Nakamura, Takeshi, Iwane, Atsuko H, Yanagida, Toshio, Imai, Hiroshi, Yu-Lee, Li-yuan, Schroer, Trina, Wynshaw-Boris, Anthony, Hirotsune, Shinji
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830693/
https://ncbi.nlm.nih.gov/pubmed/20019668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.378
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