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Kinetic Modeling Reveals a Common Death Niche for Newly Formed and Mature B Cells

BACKGROUND: B lymphocytes are subject to elimination following strong BCR ligation in the absence of appropriate second signals, and this mechanism mediates substantial cell losses during late differentiation steps in the bone marrow and periphery. Mature B cells may also be eliminated through this...

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Autors principals: Shahaf, Gitit, Cancro, Michael P., Mehr, Ramit
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830485/
https://ncbi.nlm.nih.gov/pubmed/20209168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009497
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