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Kinetic Modeling Reveals a Common Death Niche for Newly Formed and Mature B Cells

BACKGROUND: B lymphocytes are subject to elimination following strong BCR ligation in the absence of appropriate second signals, and this mechanism mediates substantial cell losses during late differentiation steps in the bone marrow and periphery. Mature B cells may also be eliminated through this...

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Detalhes bibliográficos
Main Authors: Shahaf, Gitit, Cancro, Michael P., Mehr, Ramit
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830485/
https://ncbi.nlm.nih.gov/pubmed/20209168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009497
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