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Glycoprotein D actively induces rapid internalization of two nectin-1 isoforms during herpes simplex virus entry
Entry of herpes simplex virus (HSV) occurs either by fusion at the plasma membrane or by endocytosis and fusion with an endosome. Binding of glycoprotein D (gD) to a receptor such as nectin-1 is essential in both cases. We show that virion gD triggered the rapid down-regulation of nectin-1 with kine...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2830393/ https://ncbi.nlm.nih.gov/pubmed/20089288 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2009.12.034 |
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