CHOP-independent apoptosis and pathway-selective induction of the UPR in developing plasma cells

Upon antigen stimulation, B lymphocytes differentiate into antibody secreting cells (ASC), most of which undergo apoptosis after a few days of intense Ig production. Differentiation entails expansion of the endoplasmic reticulum (ER) and requires XBP1 but not other elements of the unfolded protein r...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Masciarelli, Silvia, Fra, Anna M., Pengo, Niccoló, Bertolotti, Milena, Cenci, Simone, Fagioli, Claudio, Ron, David, Hendershot, Linda M, Sitia, Roberto
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2009
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830287/
https://ncbi.nlm.nih.gov/pubmed/20044139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2009.12.003
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