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Synthesis of γ,δ-Unsaturated Glycolic Acids via Sequenced Brook and Ireland-Claisen Rearrangements

[Image: see text] Organozinc, magnesium, and lithium nucleophiles initiate a Brook/Ireland-Claisen rearrangement sequence of allylic silyl glyoxylates resulting in formation of γ,δ-unsaturated α-silyloxy acids.

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Bibliografiske detaljer
Main Authors: Schmitt, Daniel C., Johnson, Jeffrey S.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830285/
https://ncbi.nlm.nih.gov/pubmed/20143793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol9029353
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