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Plasma Membrane Expression of Gonadotropin-Releasing Hormone Receptors: Regulation by Peptide and Nonpeptide Antagonists

Gonadotropin-releasing hormone acts via cell surface receptors but most human (h) GnRH receptors (GnRHRs) are intracellular. A membrane-permeant nonpeptide antagonist [(2S)-2-[5-[2-(2-axabicyclo[2.2.2]oct-2-yl)-1,1-dimethy-2-oxoethyl]-2-(3,5-dimethylphenyl)-1H-indol-3-yl]-N-(2-pyridin-4-ylethyl)prop...

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Detalhes bibliográficos
Main Authors: Finch, Ann R., Caunt, Christopher J., Armstrong, Stephen P., McArdle, Craig A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830153/
https://ncbi.nlm.nih.gov/pubmed/20009083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2009-0343
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