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Structural basis for lack of E2 interaction in the RING of TRAF2

TRAF proteins are intracellular signal transducers for a number of immune receptor superfamilies. Specifically, TRAF2 interacts with members of the TNF receptor superfamily and connects the receptors to downstream signaling proteins. It has been assumed that TRAF2 is a ubiquitin ligase like TRAF6 an...

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Autors principals: Yin, Qian, Lamothe, Betty, Darnay, Bryant G., Wu, Hao
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830148/
https://ncbi.nlm.nih.gov/pubmed/19810754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901462e
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