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Structure, interactions, and dynamics of the RING domain from human TRAF6
A key step in the signaling cascade responsible for activation of the transcription factor NF-κB involves Lys63-linked polyubiquitination of TRAF6. Covalent attachment of ubiquitin (Ub) to TRAF6, and subsequent poly(Ub) chain synthesis, is catalyzed by the hUev1a–hUbc13 heterodimer. hUbc13 is a cata...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2203345/ https://ncbi.nlm.nih.gov/pubmed/17327397 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.062358007 |
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