Crystal structure of TRAF1 TRAF domain and its implications in the TRAF1-mediated intracellular signaling pathway

TNF-receptor associated factor (TRAF) proteins are key adaptor molecules containing E3 ubiquitin ligase activity that play a critical role in immune cell signaling. TRAF1 is a unique family of TRAF lacking the N-terminal RING finger domain. TRAF1 is an important scaffold protein that participates in...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Kim, Chang Min, Choi, Jae Young, Bhat, Eijaz Ahmed, Jeong, Jae-Hee, Son, Young-Jin, Kim, Sunghwan, Park, Hyun Ho
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4858697/
https://ncbi.nlm.nih.gov/pubmed/27151821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25526
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