Altered eosinophil profile in mice with ST6Gal-1 deficiency: an additional role for ST6Gal-1 generated by the P1 promoter in regulating allergic inflammation

Cumulative evidence indicates that the sialyltransferase ST6Gal-1 and the sialyl-glycans, which it constructs, are functionally pleiotropic. Expression of the ST6Gal-1 gene is mediated by six distinct promoter/regulatory regions, and we hypothesized that these promoters may be used differentially to...

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Bibliographic Details
Main Authors: Nasirikenari, Mehrab, Chandrasekaran, E. V., Matta, Khushi L., Segal, Brahm H., Bogner, Paul N., Lugade, Amit A., Thanavala, Yasmin, Lee, James J., Lau, Joseph T. Y.
Format: Artigo
Language:Inglês
Published: The Society for Leukocyte Biology 2010
Subjects:
Inflammation, Extracellular Mediators, & Effector Molecules
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830128/
https://ncbi.nlm.nih.gov/pubmed/20007243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1108704
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