Anti-inflammatory IgG Production Requires Functional P1 Promoter in β-Galactoside α2,6-Sialyltransferase 1 (ST6Gal-1) Gene

The anti-inflammatory properties associated with intravenous immunoglobulin therapy require the sialic acid modification of the N-glycan of the Fc domain of IgG. Sialylation of the Fc fragment is mediated by β-galactoside α2,6-sialyltransferase 1 (ST6Gal-1), acting on the Gal(β4)GlcNAc terminal stru...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Jones, Mark B., Nasirikenari, Mehrab, Lugade, Amit A., Thanavala, Yasmin, Lau, Joseph T. Y.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2012
Témata:
Glycobiology and Extracellular Matrices
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346113/
https://ncbi.nlm.nih.gov/pubmed/22427662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.345710
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky