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Altered granulopoietic profile and exaggerated acute neutrophilic inflammation in mice with targeted deficiency in the sialyltransferase ST6Gal I

Elevation of serum sialic acid and the ST6Gal-1 sialyltransferase is part of the hepatic system inflammatory response, but the contribution of ST6Gal-1 has remained unclear. Hepatic ST6Gal-1 elevation is mediated by P1, 1 of 6 promoters regulating the ST6Gal1 gene. We report that the P1-ablated mous...

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Detalhes bibliográficos
Main Authors: Nasirikenari, Mehrab, Segal, Brahm H., Ostberg, Julie R., Urbasic, Ashlee, Lau, Joseph T.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Hematology 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895428/
https://ncbi.nlm.nih.gov/pubmed/16849643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-04-014779
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