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Leukocyte‐borne α(1,3)‐fucose is a negative regulator of β(2)‐integrin‐dependent recruitment in lung inflammation

Leukocyte recruitment in inflammation is a multistep, sequential cascade where the initial step is the selectin‐dependent tethering, followed by the formation of firmer integrin‐mediated adhesive forces leading to extravasation. The α(1,3)‐fucose‐containing sialyl‐Lewis X (sLe(X)) is the archetypica...

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Detalhes bibliográficos
Publicado no:J Leukoc Biol
Main Authors: Buffone, Alexander, Nasirikenari, Mehrab, Manhardt, Charles T., Lugade, Amit, Bogner, Paul N., Sackstein, Robert, Thanavala, Yasmin, Neelamegham, Sriram, Lau, Joseph T. Y.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608008/
https://ncbi.nlm.nih.gov/pubmed/27566832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.3A0516-215RR
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