A carregar...
The chaperonin TRiC controls polyglutamine aggregation and toxicity through subunit-specific interactions
Misfolding and aggregation of proteins containing expanded polyglutamine repeats underlie Huntington’s disease and other neurodegenerative disorders1. Here, we show that the hetero-oligomeric chaperonin TRiC (also known as CCT) physically interacts with polyglutamine-expanded variants of huntingtin...
Na minha lista:
| Main Authors: | , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2829982/ https://ncbi.nlm.nih.gov/pubmed/16980959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1477 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|