טוען...
The chaperonin TRiC controls polyglutamine aggregation and toxicity through subunit-specific interactions
Misfolding and aggregation of proteins containing expanded polyglutamine repeats underlie Huntington’s disease and other neurodegenerative disorders1. Here, we show that the hetero-oligomeric chaperonin TRiC (also known as CCT) physically interacts with polyglutamine-expanded variants of huntingtin...
שמור ב:
| Main Authors: | , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2006
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2829982/ https://ncbi.nlm.nih.gov/pubmed/16980959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1477 |
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