Phase 1 Trial of the Dengue Virus Type 4 Vaccine Candidate rDEN4Δ30-4995 in Healthy Adult Volunteers

rDEN4Δ30-4995 is a live attenuated dengue virus type 4 (DENV4) vaccine candidate specifically designed as a further attenuated derivative of the rDEN4Δ30 parent virus. In a previous study, 5 of 20 vaccinees who received 10(5) plaque-forming units (PFU) of rDEN4Δ30 developed a transient elevation of...

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Main Authors: Wright, Peter F., Durbin, Anna P., Whitehead, Stephen S., Ikizler, Mine R., Henderson, Susan, Blaney, Joseph E., Thumar, Bhavin, Ankrah, Sharon, Rock, Michael T., McKinney, Brett A., Murphy, Brian R., Schmidt, Alexander C.
Format: Artigo
Language:Inglês
Published: 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829759/
https://ncbi.nlm.nih.gov/pubmed/19861619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4269/ajtmh.2009.09-0131
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