Unstable Hemoglobins: The Role of Heme Loss in Heinz Body Formation
Mutant, unstable hemoglobins precipitate as Heinz bodies in circulating red blood cells resulting in their premature hemolysis. We stress that generally these hemoglobins contain amino acid substitutions in the β-chain of globin near the heme pocket, and demonstrate that heme binding suffers thereby...
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| Опубликовано в:: | Proc Natl Acad Sci U S A |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
1970
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282962/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5267148/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.65.3.697 |
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