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Unstable Hemoglobins: The Role of Heme Loss in Heinz Body Formation

Mutant, unstable hemoglobins precipitate as Heinz bodies in circulating red blood cells resulting in their premature hemolysis. We stress that generally these hemoglobins contain amino acid substitutions in the β-chain of globin near the heme pocket, and demonstrate that heme binding suffers thereby...

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Autors principals: Jacob, Harry, Winterhalter, Kaspar
Format: Artigo
Idioma:Inglês
Publicat: 1970
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC282962/
https://ncbi.nlm.nih.gov/pubmed/5267148
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