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Unstable Hemoglobins: The Role of Heme Loss in Heinz Body Formation

Mutant, unstable hemoglobins precipitate as Heinz bodies in circulating red blood cells resulting in their premature hemolysis. We stress that generally these hemoglobins contain amino acid substitutions in the β-chain of globin near the heme pocket, and demonstrate that heme binding suffers thereby...

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Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Jacob, Harry, Winterhalter, Kaspar
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 1970
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282962/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5267148/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.65.3.697
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