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Unstable Hemoglobins: The Role of Heme Loss in Heinz Body Formation

Mutant, unstable hemoglobins precipitate as Heinz bodies in circulating red blood cells resulting in their premature hemolysis. We stress that generally these hemoglobins contain amino acid substitutions in the β-chain of globin near the heme pocket, and demonstrate that heme binding suffers thereby...

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Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Jacob, Harry, Winterhalter, Kaspar
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 1970
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282962/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5267148/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.65.3.697
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