Pyk2 uncouples metabotropic glutamate receptor G protein signaling but facilitates ERK1/2 activation

Group I metabotropic glutamate receptors (mGluRs) are coupled via Gα(q/11 )to the activation of phospholipase Cβ, which hydrolyzes membrane phospholipids to form inositol 1,4,5 trisphosphate and diacylglycerol. This results in the release of Ca(2+ )from intracellular stores and the activation of pro...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Nicodemo, Alexander A, Pampillo, Macarena, Ferreira, Lucimar T, Dale, Lianne B, Cregan, Tamara, Ribeiro, Fabiola M, Ferguson, Stephen SG
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829546/
https://ncbi.nlm.nih.gov/pubmed/20180987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-3-4
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker