Modulation of Advanced Glycation Endproduct Synthesis by Kynurenines in Human Lens Proteins

Human lens proteins (HLP) become chemically modified by kynurenines and advanced glycation end products (AGEs) during aging and cataractogenesis. We investigated the effects of kynurenines on AGE synthesis in HLP. We found that incubation with 5 mM ribose or 5 mM ascorbate produced significant quant...

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Autori principali: Nagaraj, Ram H., Padmanabha, Smitha, Mailankot, Maneesh, Mun, Liew Jun, Glomb, Marcus A., Linetsky, Mikhail D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829369/
https://ncbi.nlm.nih.gov/pubmed/20026434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2009.12.008
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